Identification of PSD-95 in the Postsynaptic Density Using MiniSOG and EM Tomography

Identification of PSD-95 in the Postsynaptic Density Using MiniSOG and EM Tomography
May 2, 2020 0 Comments

Combining tomography with electron microscopy (EM) produces photos at definition adequate to visualise particular person protein molecules or molecular complexes in intact neurons. When freeze-substituted hippocampal cultures in plastic sections are imaged by EM tomography, detailed buildings rising from 3D reconstructions reveal putative glutamate receptors and membrane-associated filaments containing scaffolding proteins akin to postsynaptic density (PSD)-95 household proteins primarily …